Alchemy is an ability.


  • A master alchemist, Diablo begins each Quest with a selection of Concoctions ready to be brewed. Throwing Light Attacks allows Diablo to switch which Concoction to brew. By finishing a combo with a Medium attack, Diablo begins brewing the selected Concoction.
  • Once the Concoction has Brewed for 3 seconds, Diablo may dash back and hold block for 1.2 seconds to drink it. A new Concoction can’t be brewed until the first is consumed.
  • If Diablo drinks a Concoction while the matching Concoction effect is still active, he instead Poisons himself, dealing 731 direct damage over 8 seconds and reducing healing effects by 30%.



For 12 seconds, attacks deal a burst of additional Energy Damage equal to 55% of the damage dealt plus an additional 20% for each Buff the opponent has.


Gain 110% of a bar of Power over 12 seconds and allow basic attacks a 25% chance to Nullify for that duration.


Recover 848 Health when consumed and increases Regeneration rate by 25% for 12 seconds.


Gain +957 attack and Stun Immunity for 12 seconds.

List of Champions with Alchemy


List of Abilities
AberrationAcrobatic CombatAftershockAlchemyAmmo StockpileAnte UpAptitudeArmorArmor BreakArmor ShatteredArmor UpAuto-BlockBamfBehemoth BustersBerserker RageBinary IgnitionBleedBleed ImmunityBleed ResistanceBloodgem ProtectionBuff StealCauterizeChi StrikeCleanseCold ImmunityColdsnapCombo ShieldConcussionCosmic Control RodCosmic RadiationCrit BoostCritical BleedCritical DamageCrowd ExcitementCrueltyCurseCyttorak's FavorDamage ReflectionDanger SenseDazeDeath FactorDeath FieldDeformationDegenerationDirect DamageDisorientDistractionElement GunEnergy AbsorptionEnergy DamageEnergy ResistanceEnervateEnervating FieldEnfeebleEnhanced MunitionsEvadeEvil's BaneEvocationExhaustionExploit WeaknessFalterFate SealFatigueFeedbackFinal StrikeFluxForce FieldFreestyle CombatFrostbiteFuryFury's FuryGambler's RuinGenetic MemoryGlaive's ImmunityGlancingHeal BlockHellfire RoundsHex MagicIMPERIUS REXISO LoaderIce TempestIgniteIncinerateIndestructibleInjureInternal BleedIntimidating PresenceInvisibilityJudgmentKinetic PotentialKree PhysiologyLife StealLightning ArcLightning TempestLuckLunar PhasesMagnetismMartial FocusMolecular ArmorMolecular RegenerationNano-TechNeurotoxinNova FlameNullifyOm NomOrganic IceOutrageOverpowerOverrunPacifismPerfect BlockPersistent ChargePersistent CrueltyPersistent PowerPetrifyPhasingPhysical ResistancePlasma Build UpPlasma ChargePoisePoisonPoison ImmunityPoison ResistancePower BurnPower CosmicPower DrainPower GainPower LeechPower LockPower RatePower StealPower StingPre-Fight AbilityPrecisionProwessPummelPurifyQuack-FuRageReconReflect StunReflective ArmorRegenerationReplicateRhino ChargeRoboticsRock AnatomyRock ShieldRock StacksRoutRunic SpellsSabotageSafeguardScorchSelf-RepairSensory WeaveShield SystemShockSlowSoul BarbSoul HarvestSoul ImprisonmentSpirit VenomStaggerStatic ShockStifleStunStun ImmunitySymbiote StealthTauntTechno-Organic Transmode VirusTemperatureTenacityThanos' FavorTippy-ToeToxic ArmorTraumaTrue AccuracyTrue StrikeCategory:UnblockableUnstoppableVulnerabilityWeaknessWidow's Insight
Pre-Fight Abilities:
Blessings of the RealmDigi-SoulsFlame On!Prepared for AnythingS.H.I.E.L.D. Web-ShootersTempestsThe Best Defense...
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