A Class is a Champion type. There are Seven Classes in total, and every Class has an advantage over another (called a "Class Bonus") and a disadvantage to another. The seventh class, Combined, has a Class Bonus against all other Classes. However, it is exclusive to several Unplayable Champions and one Temporary Champion (the Summoned Symbioid and the now Summoned Symbiote).
List of Classes[]
Cosmic 
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Cosmic Champions are characters that are alien or can be found in space. Cosmic Champions have a Class Bonus against Tech Champions, but are weak to Mystic Champions.
| List of Cosmic Champions
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Playable: Adam Warlock ● Air-Walker ● Angela ● Annihilus ● Anti-Venomoid ● Beta Ray Bill ● Black Bolt ● Captain Marvel ● Captain Marvel (Classic) ● Carnage ● Corvus Glaive ● Cosmic Ghost Rider ● Cull Obsidian ● Dark Phoenix ● Doombot ● Drax ● Galan ● Gamora ● Gladiator ● Gorr ● Groot ● Heimdall ● Hela ● Henchpool ● Hercules ● Hulkling ● Hyperion ● Ikaris ● Karolina Dean ● King Groot ● King Groot (Deathless) ● Knull ● Maestro (Cosmic) ● Medusa ● Ms. Marvel ● Ms. Marvel (Kamala Khan) ● Nova ● Odin ● Phoenix ● Proxima Midnight ● Red Goblin ● Ronan ● Scream ● Sentinelbot ● Sersi ● Silver Surfer ● Spider-Man (Symbiote) ● Super-Skrull ● Superior Iron Man ● Symbioid ● Terrax ● Thanos ● Thanos (Deathless) ● The Champion ● The Serpent ● Thor ● Venom ● Venom the Duck ● Venompool ● Vision (Aarkus) ● Vox
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Mutant 
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Mutant Champions are, as the name suggests, mutants. Mutant Champions have a Class Bonus against Skill Champions, but are weak to Tech Champions.
 List of Mutant Champions
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Playable: Anti-Venomoid ● Apocalypse ● Archangel ● Beast ● Bishop ● Cable ● Captain Britain ● Cassandra Nova ● Colossus ● Cyclops (Blue Team) ● Cyclops (New Xavier School) ● Dani Moonstar ● Dazzler ● Deadpool ● Deadpool (X-Force) ● Domino ● Doombot ● Dust ● Emma Frost ● Gambit ● Gentle ● Goldpool ● Havok ● Henchpool ● Iceman ● Jean Grey ● Jubilee ● Kitty Pryde ● Magneto ● Magneto (House of X) ● Mister Sinister ● Namor ● Negasonic Teenage Warhead ● Nightcrawler ● Northstar ● Old Man Logan ● Omega Red ● Onslaught ● Platinumpool ● Professor X ● Psylocke ● Rogue ● Sabretooth ● Sauron ● Sentinelbot ● Silver Samurai ● Storm ● Storm (Pyramid X) ● Stryfe ● Sunspot ● Symbioid ● Toad ● Wolverine ● Wolverine (Weapon X) ● Wolverine (X-23)
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Mystic []
Mystic Champions are characters associated with mysticism or magic. Mystic Champions have a Class Bonus against Cosmic Champions, but are weak to Science Champions.
Science []
Science Champions are characters that have been scientifically altered in some way. Science Champions have a Class Bonus against Mystic Champions, but are weak to Skill Champions.
Skill []
Skill Champions are characters who are good at fighting without using excessive special powers. Skill Champions have a Class Bonus against Science Champions, but are weak to Mutant Champions.
 List of Skill Champions
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Playable: Ægon ● Agent Venom ● Anti-Venomoid ● Attuma ● Baron Zemo ● Black Cat ● Black Panther ● Black Panther (Civil War) ● Black Widow ● Black Widow (Deadly Origin) ● Blade ● Bullseye ● Chee'ilth ● Crossbones ● Daredevil (Classic) ● Daredevil (Hell's Kitchen) ● Doombot ● Elektra ● Elsa Bloodstone ● Falcon ● Franken-Castle ● Gwenpool ● Hawkeye ● Henchpool ● Hit-Monkey ● Jabari Panther ● Karnak ● Kate Bishop ● Killmonger ● Kingpin ● Korg ● Kraven ● Lumatrix ● Mantis ● Masacre ● Misty Knight ● Mole Man ● Moon Knight ● Moondragon ● Mr. Knight ● Nick Fury ● Night Thrasher ● Okoye ● Patriot ● Punisher ● Ronin ● Shang-Chi ● Sentinelbot ● Silver Sable ● Spider-Man (Stealth Suit) ● Squirrel Girl ● Symbioid ● Taskmaster ● Thor (Ragnarok) ● Valkyrie ● Winter Soldier ● Yelena Belova
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Tech []
Tech Champions are characters who are either androids or rely on technology to fight. Tech Champions have a Class Bonus against Mutant Champions, but are weak to Cosmic Champions.
 List of Tech Champions
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Playable: Ant-Man (Future) ● Anti-Venomoid ● Arcade ● Arnim Zola ● Bastion ● Captain America (Sam Wilson) ● Civil Warrior ● Darkhawk ● Doctor Octopus ● Doombot ● Ghost ● Green Goblin ● Guardian ● Guillotine 2099 ● Henchpool ● Howard the Duck ● Hulkbuster ● Iron Man ● Iron Man (Infamous) ● Iron Man (Infinity War) ● Iron Patriot ● Ironheart ● Jack O'Lantern ● Kang the Conqueror ● Lady Deathstrike ● Mysterio ● Nebula ● Nimrod ● Omega Sentinel ● Peni Parker ● Prowler ● Psycho-Man ● Punisher 2099 ● Red Skull ● Rocket Raccoon ● Sentinel ● Sentinelbot ● Shocker ● Shuri ● Silver Centurion ● Solvarch ● Spider-Man (Stark Enhanced) ● Star-Lord ● Symbioid ● The Maker ● Ultron ● Ultron (Classic) ● Vision ● Vision (Age of Ultron) ● Vision (Deathless) ● Viv Vision ● Vulture ● War Machine ● Warlock ● Yondu
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