Degeneration

Degeneration
Type	Debuff, Passive, Instant
Nature	Detrimental, Damaging
Description	Deals Direct Damage while active.
Template

Degeneration is a Damaging detrimental effect that deals Direct Damage while active.

As it deals Direct Damage, Degeneration ignores Armor, Physical Resistance and Energy Resistance. Degeneration Resistance can reduce incoming Degeneration damage, while Degeneration Vulnerability can increase incoming Degeneration damage.

List of Champions with Degeneration

Debuff

• Base Abilities
  • Apocalypse
  • Cable
  • Cosmic Ghost Rider - Damnation
  • Gamora - When fighting #Robot Champions
  • Ghost Rider - Damnation
  • Gorr
  • Guillotine
  • Guillotine (Deathless)
  • Guillotine 2099
  • Kindred
  • Kingpin
  • Knull
  • Kushala
  • Magneto (House of X)
  • Mister Negative
  • Mister Sinister
  • Mordo
  • Omega Red
  • Purgatory
  • The Leader - Severe Debuff
  • Ultron
  • Venompool
  • Void
  • Vox
  • Wiccan

• Synergies
  • #Spider-Verse Heroes - Mister Negative "From Light to Dark" Synergy
  • Captain Britain - with Psylocke
  • Mister Sinister - with Havok
  • Psylocke - with Captain Britain
  • Thor (Jane Foster) - with Absorbing Man

Passive

• Base Abilities
  • Doombot
  • Dormammu
  • Dracula - Normal and Dire Degeneration
  • Dragon Man
  • Ebony Maw
  • Elsa Bloodstone
  • Isophyne
  • Kindred
  • Kushala
  • Mojo
  • Onslaught
  • Sauron
  • Scarlet Witch
  • Sentinelbot
  • The Destroyer
  • Venom the Duck
  • Warlock

• Synergies
  • Dormammu - with Doctor Strange
  • Isophyne - with Lumatrix, Solvarch, and Imperiosa
  • Spider-Slayer (J. Jonah Jameson) - with Mojo
  • Thor (Jane Foster) - with Absorbing Man

Instant

• Base Abilities
  • Kindred
  • Omega Red
  • The Leader
  • Vision (Deathless)

• Synergies
  • Longshot - with Mojo
  • Rogue - with Longshot

• On Self
  • Henchpool

List of Champions that counter Degeneration

Immunity

• Synergies
  • Lady Deathstrike - with Spiral, while Nanobots Regenerator is active

Resistance

• Base Abilities
  • Count Nefaria - Up to 90% based on Ionic Charges
  • Daredevil (Hell's Kitchen) - Up to 100%, 0.2 seconds after striking while in Stick's Apprentice Mode
  • Hulk - Up to 90% based on missing Health
  • Gambit - 100%, 0.2 seconds after striking with Medium, Heavy or Special Attacks, Passive Degeneration only
  • Knull - 40%
  • Mister Negative - 40% per Unique Debuff on the Opponent
  • Moondragon - 30%, plus an additional flat 50% while Psionic Transcendence is active, Degenerations from Champions or Quest Buffs only
  • Omega Red - 100%, 0.2 seconds after striking with Tentacle Hits, Passive Degeneration only
  • Spider-Ham - 15% per Spider-Nonsense

• Synergies
  • #Dimensional Beings - 25%, America Chavez "Out of This World" Synergy
  • Photon - 20% per unique Debuff on the Opponent, with Mister Negative
  • Quicksilver - 8.3% per 100 Momentum Charges, with Wiccan
  • Silk - 30% per unique Synergy Champion on the team, with Spider-Gwen or Spider-Man (Miles Morales)
  • Spider-Gwen - 30% per unique Synergy Champion on the team, with Silk
  • Spider-Man (Miles Morales) - 30% per unique Synergy Champion on the team, with Silk

Purify (Specific to Degeneration Debuffs)

• Synergies
  • Doctor Doom - 50% - with Doctor Strange or Symbiote Supreme, when activating Aura of Haazareth

Gallery

Degeneration Passive

Degeneration Debuff

Severe Debuff - Degeneration

Trivia

• Degeneration has the opposite effect of Regeneration, which recovers Health over time.
• Degeneration was introduced as an uncounterable damage over time effect and is commonly used in Nodes. To this date, no Champion is fully immune to Degeneration.

Navigation

[v • e] Terminology and List of Abilities

Buffs and Beneficial Effects [v ● e] General Buffs: Amplify ● Aptitude ● Armor Up ● Auto-Block ● Berserk ● Brace ● Bulwark ● Combat Power Rate ● Combo Shield ● Critical Resistance ● Cruelty ● Death Immunity ● Debuff Immunity ● Endurance ● Energize ● Energy Protection ● Energy Resistance ● Evasion ● Expertise ● Extend ● Fervor ● Flourish ● Fortitude ● Fury ● Glancing ● Grit ● Immortality ● Impact ● Indestructible ● Indestructible Charge ● Instinct ● Intensify ● Invisibility ● Jiggy With It ● Perfect Block ● Physical Resistance ● Pierce ● Placebo Buff ● Power Efficiency ● Power Gain (Power Flood) ● Precision ● Protection ● Prowess ● Pursuit ● Rampage ● Regeneration (Life Steal ● Self-Repair) ● Rejuvenate ● Resist Shock ● Resistance Up ● Resonance ● Safeguard ● Steadfast ● Stoicism ● Stun Immune ● True Accuracy ● True Damage ● True Focus ● True Sense ● True Strike ● Unblockable ● Uncanny ● Undermine ● Unstoppable ● Vicious ● Vigilance ● Vigor Champion-Specific Buffs: Bionic Overcharge ● Confidence ● Cosmic Control Rod ● Cosmic Energy Overload ● Cosmic Radiation ● Dimensional Link ● Empowered Dimensional Link ● Frozen Air ● Gift of the Loa ● Hunter-Spider ● Ignition ● Iridescence ● Klyntar Mutation ● Malice ● Nova Fists ● Nova Surge ● Overpower ● Pentacle ● Phase ● Plasma Aura ● Power Charge ● Power Cosmic ● Power of Galactus ● Rout ● Sovereignty ● Thanos' Favor ● Transmutation ● Venom Magic ● Viscera Magic ● Volt Magic Buffs inflicted on Opponent: Detonate ● Hater ● Ignition ● Loa ● Rubble ● Spider-Seal ● Toxic Armor ● Toxic Pustule Passives: Aspect of Evolution ● Block Penetration ● Cleanse ● Counterpunch Charge ● Cunning ● Embolden ● Energy Penetration ● Haste ● Heavy Proficiency ● Inexorable ● Invulnerable ● Lying In Hate ● Miss ● Protection ● Reinforce ● Reverb ● Smoulder ● Stimulate ● Trample ● Undying ● Untouchable ● Vitality ● Vitalize ● Zeal Instant Effects: Auto-Block ● Dodge ● Evade ● Glance ● Miss ● Purify (Tenacity) ● Reversal Retired: Luck Debuffs and Detrimental Effects [v ● e] Damaging Debuffs: Bleed ● Coldsnap ● Corrosion ● Curse ● Degeneration (Damnation) ● Disintegration ● Incinerate ● Neuroshock ● Plasma ● Poison ● Power Burn ● Rupture ● Shock ● Soul Barb Non-Damaging Debuffs: Agility ● Armor Break ● Armor Shattered ● Atrophy ● Beeper ● Bleed Vulnerability ● Buff Immunity ● Busted ● Charm ● Combo Detonation ● Concussion ● Cowardice ● Crush ● Daunted ● Debilitate ● Debuff Siphon ● Decelerate ● Degeneration Vulnerability ● Delirium ● Devolve ● Disorient ● Distraction ● Energy Vulnerability ● Enervate ● Ensnare ● Exhaustion ● Falter ● Fate Seal ● Fatigue ● Fear ● Fragility ● Fumble ● Halt ● Heal Block ● Hinder ● Ineptitude ● Infuriate ● Injury ● Intimidate ● Neutralize ● Overload ● Panic ● Petrify ● Physical Vulnerability ● Power Detonation ● Power Dissolve ● Power Drain ● Power Lock ● Power Steal ● Power Sting ● Retribution ● Root ● Sabotage ● Shock Vulnerability ● Shrivel ● Slow ● Smother ● Special Concussion ● Special Lock ● Special Weakness ● Spectre ● Stagger ● Stifle ● Stun ● Sunder ● Suppression ● Taunt ● Torment ● Tracking ● Tranquilize ● Trauma ● Unsteady ● Vulnerability ● Weakness ● Whiplash ● Wither Champion-Specific Debuffs: Bleed Curse ● Careful Study ● Dark Sting ● Decreased Combat Power Rate ● Energy Build Up ● Feedback ● Klyntar Debuff ● Living Abyss ● Organic Magnetism ● Pain Link ● Plasma Build Up ● Rage ● Resolve ● Sand ● Siphon Burn ● Siphon Charge ● The Dark Tide ● Transfix Passives: Acid Burn ● Caltrops ● Critical Failure ● Disarm ● Disintegration Vulnerability ● Essence Steal ● Frostbite ● Incinerate Vulnerability ● Instants Siphon ● Inverted Controls ● Magnetized ● Marked ● Neurotoxin ● Never Back Down ● Nova Flame ● Power Reroute ● Sleep ● Special 1 Lock ● Special 2 Lock ● Special Power Drain ● Spirit Drain ● Striker Opening Other Detrimental Effects: Buff Steal ● Destroy ● Invalidate ● Nullify ● Om Nom ● Pulverize Retired: Black ISO-8 ● Daze ● Heal Reversal (Phantasm) ● Hex (Fate Seal) ● Hex Vulnerability ● Paralyze ● Power Leech ● Thermal Feedback ● Thunderquack ● Vulnerability (Fragility) All Abilities Aberration ● Acid Burn ● Acrobatic Combat ● Aftershock ● Agility ● Alchemy ● Ammo Stockpile ● Amplify ● Ante Up ● Aptitude ● Armor ● Armor Break ● Armor Shattered ● Armor Up ● Aspect of Evolution ● Atrophy ● Auto-Block ● Bamf ● Beeper ● Behemoth Busters ● Berserk ● Berserker Rage ● Binary Ignition ● Black ISO-8 ● Bleed ● Bleed Curse ● Bleed Vulnerability ● Blessings of the Realm ● Block Penetration ● Bloodgem Protection ● Brace ● Buff Immunity ● Buff Steal ● Bulwark ● Busted ● Caltrops ● Careful Study ● Cauterize ● Charm ● Chi Strike ● Cleanse ● Coldsnap ● Combat Power Rate ● Combo Detonation ● Combo Shield ● Concussion ● Confidence ● Corrosion ● Cosmic Control Rod ● Cosmic Radiation ● Counterpunch Charge ● Cowardice ● Critical Failure ● Critical Resistance ● Crowd Excitement ● Cruelty ● Crush ● Cunning ● Curse ● Cyttorak's Favor ● Damage Reflection ● Damnation ● Danger Sense ● Dark Sting ● Dark Tide ● Daunted ● Daze ● Death Factor ● Death Field ● Death Immunity ● Debilitate ● Debuff Immunity ● Debuff Siphon ● Decelerate ● Decreased Combat Power Rate ● Deformation ● Degeneration ● Degeneration Vulnerability ● Delirium ● Destroy ● Detonate ● Devolve ● Digi-Souls ● Direct Damage ● Disarm ● Disintegration ● Disintegration Vulnerability ● Disorient ● Distraction ● Dodge (ability) ● Element Gun ● Embolden ● Endurance ● Endure ● Energize ● Energy Absorption ● Energy Damage ● Energy Protection ● Energy Resistance ● Energy Vulnerability ● Enervate ● Enervating Field ● Enhanced Munitions ● Ensnare ● Evade ● Evil's Bane ● Evocation ● Exhaustion ● Expertise ● Exploit Weakness ● Extend ● Falter ● Fate Seal ● Fatigue ● Fear ● Feedback ● Fervor ● Final Strike ● Flame On! ● Flourish ● Flux ● Force Field ● Fortitude ● Fragility ● Freestyle Combat ● Frostbite ● Fumble ● Fury ● Fury's Fury ● Gambler's Ruin ● Genetic Memory ● Glaive's Immunity ● Glance ● Glancing ● Grit ● Halt ● Haste ● Heal Block ● Heavy Proficiency ● Hellfire Rounds ● Hex Magic ● Hinder ● IMPERIUS REX ● ISO Loader ● Ice Tempest ● Ignite ● Ignition ● Immortality ● Impact ● Incinerate ● Incinerate Vulnerability ● Indestructible ● Indestructible Charge ● Ineptitude ● Inexorable ● Infuriate ● Injury ● Instants Siphon ● Instinct ● Intensify ● Internal Bleed ● Intimidate ● Intimidating Presence ● Invalidate ● Inverted Controls ● Invisibility ● Invulnerable ● Jiggy With It ● Judgment ● Kinetic Potential ● Klyntar Debuff ● Klyntar Mutation ● Kree Physiology ● Life Steal ● Lightning Arc ● Lightning Tempest ● Living Abyss ● Luck ● Lunar Phases ● Lying In Hate ● Magnetized ● Malice ● Marked ● Martial Focus ● Miss ● Molecular Armor ● Molecular Regeneration ● Nano-Tech ● Neuroshock ● Neurotoxin ● Neutralize ● Never Back Down ● Nova Flame ● Nullify ● Om Nom ● Organic Ice ● Organic Magnetism ● Organic Steel ● Outrage ● Overcharge ● Overload ● Overpower ● Overrun ● Pacifism ● Pain Link ● Panic ● Perfect Block ● Persistent Charge ● Persistent Cruelty ● Persistent Power ● Petrify ● Phasing ● Physical Damage ● Physical Resistance ● Physical Vulnerability ● Pierce ● Plasma ● Plasma Build Up ● Plasma Charge ● Poise ● Poison ● Power Burn ● Power Cosmic ● Power Detonation ● Power Dissolve ● Power Drain ● Power Efficiency ● Power Gain ● Power Leech ● Power Lock ● Power Reroute ● Power Steal ● Power Sting ● Pre-Fight Ability ● Precision ● Prepared for Anything ● Protection ● Protection (Passive) ● Prowess ● Pulverize ● Pummel ● Purify ● Pursuit ● Quack-Fu ● Rage ● Rampage ● Recon ● Reflect Stun ● Reflective Armor ● Regeneration ● Reinforce ● Rejuvenate ● Replicate ● Resist Shock ● Resistance Up ● Resonance ● Retribution ● Reverb ● Reversal ● Rhino Charge ● Robotics ● Rock Anatomy ● Rock Shield ● Rock Stacks ● Root ● Rout ● Runic Spells ● Rupture ● S.H.I.E.L.D. Web-Shooters ● Sabotage ● Safeguard ● Sand ● Scorch ● Self-Repair ● Sensory Weave ● Shbleed Dooboof ● Shield System ● Shock ● Shock Vulnerability ● Shrivel ● Siphon Burn ● Siphon Charge ● Sleep ● Slow ● Smother ● Smoulder ● Soul Barb ● Soul Harvest ● Soul Imprisonment ● Special 1 Lock ● Special 2 Lock ● Special Concussion ● Special Lock ● Special Power Drain ● Special Weakness ● Spectre ● Spell ● Spirit Drain ● Stagger ● Static Shock ● Steadfast ● Stifle ● Stimulate ● Stoicism ● Stun ● Stun Immunity ● Sunder ● Suppression ● Symbiote Stealth ● Taunt ● Techno-Organic Transmode Virus ● Temperature ● Tempests ● Tenacity ● Thanos' Favor ● The Best Defense... ● Thunderquack ● Tippy-Toe ● Torment ● Toxic Armor ● Tracking ● Trample ● Tranquilize ● Transfix ● Trauma ● True Accuracy ● True Damage ● True Focus ● True Sense ● True Strike ● Unblockable ● Uncanny ● Undermine ● Undying ● Unsteady ● Unstoppable ● Untouchable ● Vicious ● Vigilance ● Vigor ● Vitality ● Vitalize ● Vulnerability ● Weakness ● Whiplash ● Widow's Insight ● Wither ● Zeal Pre-Fight Abilities: Blessings of the Realm ● Digi-Souls ● Flame On! ● Prepared for Anything ● S.H.I.E.L.D. Web-Shooters ● Tempests ● The Best Defense...