Mister Sinister

Portrait
Featured

Base Attributes

Release Date

February 11th, 2019^[1]

Origin

Marvel Comics
First Appearance: Uncanny X-Men #213 (1987)

Abilities

Molecular Regeneration
Concussion
Stun
Power Steal

Signature Ability

Engineered Perfection

Availability

No

Yes (exclusive)

Yes

Yes (exclusive)

Template

Mister Sinister is a Mutant Champion. Being a Mutant Champion, he has a Class Bonus against Skill Champions, but is weak to Tech Champions.

Bio[]

Nathaniel Essex, a scientist in the latter half of the 19th century, pledged loyalty to the mutant-demi god Apocalypse in exchange for activation of his dormant X-Factor. Donning the moniker of Mister Sinister, Essex began to engineer bloodlines in the hope of creating the perfect mutant. His attention would eventually focus on two particularly gifted children, Scott Summers and Jean Grey. In command of the Marauders, a band of mutants that follow him, Mister Sinister has been the mastermind of many schemes and plots, not the least of which was the birth of Cyclops and Madelyne Pryor’s child, Nathan Summers, also known as Cable.

Mechanics[]

Mister Sinister will live up to his name, especially as a defender. His ability to Regenerate damage taken from Critical Hits will allow this Mutant to survive some of the heaviest hits in the Contest. As a master of genetic manipulation, Mister Sinister’s other abilities allow him to improve himself while countering the abilities of his opponent.

Stats[]

Max Rating	Max Health	Max Attack
568	2715	186
-	-	-
1496	7215	494
-	-	-
3754	18092	1238
4725	-	-
7577	36276	2482
10480	-	-
12920	61898	4234
17860	-	-
32800	157221	10755
-	-	-

Abilities[]

Always Active

Mister Sinister’s Telepathic Mastery renders him Immune to Taunt and Reversed Controls.
Mister Sinister reduces the potency of incoming Bleed effects by 100%.
Mister Sinister’s Telekinetic Powers allow him to Block Unblockable Special Attacks.
Well-Timed Blocks grant a Bulwark Passive, increasing Block Proficiency by +X. Max: 5.

Tier	Block Proficiency
	188.89
	205.56
	222.22
	233.33
	250
	305.56

Whenever a Skill Champion Purifies a Debuff, reduce the Ability accuracy of their Purify Abilities by 25%, up to -100%.

Dev Notes: Mister Sinister now gains Bulwarks, and can reduce Mutant Purify chance!

Molecular Regeneration – Passive

Regeneration Rate is increased by 1% for every hit on the opponent’s Combo Meter up to 50 hits.
Mister Sinister’s Regeneration Rate cannot be reduced.
100% chance to Regenerate 70% of damage dealt by enemy Critical Hits over 0.5 seconds. Abilities cannot modify the Ability Accuracy, Duration, or Potency of this ability, aside from effects that would modify Mister Sinister’s Regeneration Rate.

Dev Notes: Bringing a Heal Blocking champion will be essential when fighting Mister Sinister when placed on complimentary AW Nodes. Another important note is that Damaging Debuffs will not trigger Sinister’s Regeneration, but run the risk of being Transferred to you as a result of his first Special Attack.

When Charging a Heavy Attack

Pauses the duration of Damaging Debuffs, Stun, Concussion, and Power Steal on the opponent.
Charging a Heavy Attack for 1 second grants a Vicious Passive, increasing the potency of Damaging Debuffs by 30% for 8 seconds.
Charging a Heavy Attack for an additional 1 second triggers Mister Sinister's Genetic Manipulation. For the next 7 seconds, he inflicts a 10 second Bleed Debuff on himself every 0.7 seconds.

Dev Notes: Utilizing Sinister’s Ability to Pause the debuffs he inflicts or Transfers will allow you to get the most from their potent effects. When paired with a Stun, it’s possible to easily gain added Critical Rating and Damage by fully charging the Heavy Attack.

Signature Ability[]

Engineered Perfection - Persistent Charge

Each time Mister Sinister defeats an opponent, he extracts their genetic code, gaining a different Passive ability for the rest of the quest depending on the defeated Champion’s Class. [Max 3 of each Passive, 10 Passives total.]
Mister Sinister starts each fight with 3 of these effects at random. These do not persist between fights and do not count toward the max Passives.
Mutant: Prowess, increasing Special Attack Damage by X%.

Tier	Special Attack Damage %
	5.01 - 30%
	5.01 - 30%
	5.01 - 30%
	10 - 30%
	10 - 30%
	10 - 30%

Skill: Precision, increasing Critical Rating by X.

Tier	Critical Rating
	88.6 - 425
	96.42 - 462.5
	104.23 - 500
	110.54 - 525
	118.43 - 562.5
	144.75 - 687.5

Science: Regen Rate, increasing Regeneration Rate by X%.

Tier	Regeneration Rate %
	4.95 - 20%
	4.95 - 20%
	4.95 - 20%
	5 - 20%
	5 - 20%
	5 - 20%

Mystic: Combat Power Rate, increasing Power Rate by X%.

Tier	Power Rate %
	4.95 - 20%
	4.95 - 20%
	4.95 - 20%
	5 - 20%
	5 - 20%
	5 - 20%

Cosmic: Fury, increasing Attack Rating by X.

Tier	Attack Rating
	9.31 - 55.8
	24.72 - 148.2
	61.96 - 371.4
	248.19 - 744.61
	423.38 - 1270.22
	1075.45 - 3226.54

Dev Notes: Mister Sinister now starts with 3 random charges of his Signature Ability! This should help him a ton in content where he can’t ramp, or to help him start his Ramp!

Special Attacks[]

Special 1 – Genetic Disruption
Mister Sinister sends a pulse of energy, infusing his opponent with faulty genetic material.

Transfer all Damaging Debuffs on Mister Sinister to non-#Robot Opponents, converting them into Degeneration Debuffs dealing X Direct Damage over 6 seconds. This ability activates even if this attack is Blocked or avoided.

Tier	Direct Damage
	167.4
	444.6
	1114.2
	2233.8
	3810.6
	9679.5

Mister Sinister inflicts himself with a non-stacking 0 potency Bleed dealing Debuff Direct Damage over 20 seconds.

Dev Notes: It’s important to remember that the Transfer of Damaging Debuffs cannot be prevented except for #Robots. Definitely reconsider bringing any epic Bleed or damage over time champions in against him unless they are a robot.

Special 2 – Genetic Negation
Disabling several important genes can render the opponent powerless, in this case, it also leaves the opponent in a catatonic state.

100% chance to inflict Concussion, reducing the opponent’s Ability Accuracy by 100% for 6 seconds. This ability activates even if this attack is Blocked or avoided.
100% chance to Stun for 2.5 second(s).

Dev Notes: Facing off against a prolific Evader? How about an enemy who likes to trigger a defensive ability when struck? Worry not, Sinister’s Special Attack will ensure those abilities don’t get in the way of this Special Attack.

Special 3 – Genetic Extraction
Once an exciting genetic structure is discovered, Mister Sinister takes great pleasure negating its beneficial effects and extracting its essence for himself.

100% chance to inflict Concussion, reducing the opponent’s Ability Accuracy by 100% for 12 seconds.
100% chance to inflict a Power Steal Debuff, stealing 20% of Max Power over 3 seconds.

Dev Notes: The culmination of Sinister’s work, make sure to Pause the Power Leech to maximize the Power he is able to steal once the attack ends.

Synergy Bonuses[]

Synergy	Partner(s)	Effect(s)
Genetic Masterpiece		All Mutant Champions: Randomly start the fight with either +25% passive Attack Rating, +25% passive Power Rate, or +25% passive Armor Rating. Unique Synergy: Does not stack with duplicate synergies.
Mutant Dominion		All Mutant Champions: +20% Passive Fury when fighting with Class Disadvantage. Unique Synergy: Does not stack with duplicate synergies.
Blood Lines		Mister Sinister, Cyclops (New Xavier School), Phoenix: During Special Attacks, gain +20% Critical Rating and a True Strike Buff. Cyclops (Blue Team): Beam hits gain +20% Critical Penetration. Unique Synergy: Does not stack with duplicate synergies.
Masterminds		Mister Sinister, Kingpin, Ultron, M.O.D.O.K.: Each time the opponent uses a Special Attack they become Power Locked for 6 seconds. Unique Synergy: Does not stack with duplicate synergies.
Incoming Synergy	Partner(s)	Effect(s)
Your Fate is Mine		Apocalypse: Start the first fight in a quest with maximum Genetic Code. Mister Sinister: Degeneration Debuffs gain +50% Potency. Unique Synergy: Does not stack with duplicate synergies.
Geneticists		Arnim Zola: Personal Disintegration Debuffs deal 20% more damage. Mister Sinister: Personal Degeneration Debuffs deal 20% less damage but gain 50% increased duration. Unique Synergy: Does not stack with duplicate synergies.
Enemies - Level 3		All Champions: +155 Critical Rating.
Peak Fashion		Synergy Champions: Block Proficiency increased by +400. Unique Synergy: Does not stack with duplicate synergies.
Enemies - Level 3		All Champions: +155 Critical Rating.
Runs in the Family		Havok: Gain 2 Plasma Charge(s) after each Special Attack. Mister Sinister: Well timed Blocking a contact attack inflicts a Degeneration Debuff, dealing 30% of Attack as Direct Damage over 1 second. Unique Synergy: Does not stack with duplicate synergies.
Rivals - Level 3		All Champions: +115 Critical Damage Rating.
Crazy Scientists		Lizard: Personal Unstoppable lasts +2 seconds. Mister Sinister: When the Opponent fails to Purify one or more Debuffs due to reduced Ability Accuracy, self-inflict a personal Bleed Debuff. Unique Synergy: Does not stack with duplicate synergies.
No More Patients		Synergy Champions: Whenever the Opponent gains a Regeneration effect, gain a non-stacking Regeneration Passive healing 2% of Max Health over 2 seconds. This goes on Cooldown for 5 seconds. When it ends, it goes on cooldown for 5 seconds. Every 4th of these Regenerations that would be gained instaed inflicts the Opponent with a Heal Block Passive for 12 seconds. Unique Synergy: Does not stack with duplicate synergies.
Enemies - Level 3		All Champions: +155 Critical Rating.
Enemies - Level 3		All Champions: +155 Critical Rating.
Intelligencia Old and New		All Champions: +5% Perfect Block Chance.

Strengths and Weaknesses[]

Strengths[]

Regeneration
- Mister Sinister has some of the most consistent and powerful Regeneration in the contest! Stand tall against the strongest opponents with tons of health.

Damage Over Time Control
- While he may not be immune to as many effects as some, he can reflect Damage Over Time effects back at the opponent and turn them into Degeneration!

Weaknesses[]

Heal Block
- While his Regeneration may be powerful, it won’t do much of anything if it’s Heal Blocked!

Robots
- Those Pesky Robots don’t have Genes for Sinister to manipulate! As such he cannot reflect Damage Over Time effects back with his Special 1 to any champion with the #Robot tag.

Recommended Masteries[]

Liquid Courage and Double Edge
- While Mister Sinister is not specifically Immune to Bleed or Poison, his first Special Attack allows him to quickly Transfer both Debuffs to his opponent.