Marvel Contest of Champions Wiki
Marvel Contest of Champions Wiki
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I desire first-hand knowledge![src]

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—Mysterio under the effects of the ISO-Spell[src]

Mysterio is a Tech Champion. Being a Tech Champion, he has a Class Bonus against Mutant Champions, but is weak to Cosmic Champions.


Quentin Beck always dreamed of making it big in the film industry. However, even as one of the most accomplished special effects designers in the business, he never received the spotlight he rightfully deserved. Craving recognition, Beck took on the persona “Mysterio”, using his expertise in special effects and illusions to become a Super-Villain with the goal of taking down a costumed hero and thus proving his capabilities to the world.


Basic Abilities


  • Mysterio's Ability Accuracy cannot be decreased and he's immune to all Poison effects. However, if knocked down by a Spider-Verse Hero or inflicted with Armor Break, his helmet is cracked for 10 seconds, temporarily disabling these benefits.

Chemical Gas (Passive)

  • Mysterio's second Medium attack generates 1 Chemical Gas, stacking up to 3 total. Gas can't be generated while his helmet is cracked.
  • Landing a Heavy Attack with 1 or more Chemical Gas consumes them and inflicts the Opponent with a single Poison Debuff, dealing X direct damage per Chemical Gas consumed over 8 seconds, and reducing health recovery by 30%.
  • While affected by Mysterio's Poison, Spider-Verse Heroes can't Evade.

On Fourth Light Attack

  • 100% chance to inflict a Heal Block Passive, preventing the Opponent from healing for 1 second(s). This duration increases by +2 seconds for each Chemical Gas Mysterio has.

Signature Ability

Lethal Gas (Passive)

  • Mysterio generates 1 Chemical Gas every X seconds.

Special Attacks

Special 1: Out of Nowhere - Mysterio fires a beam at his Opponent before dipping into his smoke, emerging in their face and delivering a powerful uppercut.

  • Mysterio gains a Reflection Gas Passive lasting 4 seconds and all his Chemical Gas is consumed, each adding 1 second to its duration.
  • If struck while Reflection Gas is active, the incoming damage is stored. Upon expiry, 70% of the taken damage is reflected onto the Opponent and Mysterio immediately Regenerates 100% of the damage he took.

Special 2: Invisible Killer - Mysterio puts his knowledge of special effects to the test, projecting a series of illusions at the opponent and disguising his whereabouts.

  • Mysterio gains an Illusion Gas Passive lasting 4 seconds and all his Chemical Gas is consumed, each adding 1 second to its duration.
  • While active, the Opponent is inflicted with a Power Drain Debuff, losing 6% of their max Power per second.
  • While active, all incoming attacks have a 25% chance to Miss, increasing to 100% while charging a Heavy Attack.

Special 3: Right Behind You - Mysterio uses his smoke cloud to fly around the opponent firing deadly beams as he goes, finally appearing behind them for a final blast.

  • Mysterio gains a Frenzy Gas Passive lasting 10 seconds and all his Chemical Gas is consumed, each adding 4 seconds to the duration.
  • While Frenzy Gas is active, Mysterio gains X Attack Rating and the potency of his Poisons are increased by 300%

Synergy Bonuses

Synergy Partner(s) Effect(s)
Mine Can Hover Night Thrasher portrait.png Mysterio: When dashing forward, Mysterio has a 70% chance to inflict the Opponent with Falter for the duration of the dash. Opponents suffering Falter have a 100% chance to Miss their attacks.
Solo: Only affects this Champion and does not stack.
Encroaching Insanity Daredevil portrait.pngDaredevil (Hell's Kitchen) portrait.png Mysterio: Poison durations are increased by 2 seconds.
Solo: Only affects this Champion and does not stack.
Enhanced Illusionist Spider-Man (Stealth Suit) portrait.png Mysterio: Reflection, Illusion, and Frenzy Gas last for an additional 2 seconds.
Solo: Only affects this Champion and does not stack.
Mental Immunity Emma Frost portrait.png Emma Frost, Mysterio: Grants immunity to reverse controls.
Unique Synergy: Does not stack with duplicate synergies.
Nemesis Spider-Gwen portrait.pngSpider-Man portrait.pngSpider-Man (Symbiote) portrait.pngSpider-Man (Miles Morales) portrait.pngSpider-Man (Stark Enhanced) portrait.pngSpider-Man (Stealth Suit) portrait.png All: All Champions gain +8% Attack

Strengths and Weaknesses


Coming Soon.


Coming Soon.

Recommended Masteries

Coming Soon.



Tech.png List of Tech Champions Tech.png

Playable: Captain America (Sam Wilson)Civil WarriorDarkhawkDoctor OctopusGhostGreen GoblinGuardianGuillotine 2099Howard the DuckHulkbusterIron ManIron Man (Infinity War)Iron PatriotKang the ConquerorMysterioNebulaNimrodOmega SentinelPeni ParkerPsycho-ManPunisher 2099Red Skull Rocket RaccoonSentinelSilver CenturionSpider-Man (Stark Enhanced)Star-LordUltronUltron (Classic)VisionVision (Age of Ultron)VultureWar MachineYonduWarlock
Not playable: Adaptoid (Hydra) ● DeadpooloidDoombotKang the ConquerorSentineloidStar-KangSymbioidUltron Drone
Upcoming: None