Weakness is a non-Damaging detrimental effect that reduces Attack Rating. It is commonly found in Science
Champions.
It has the opposite effect of Fury, which increases Attack Rating.
List of Champions with Weakness[]
Debuff[]
- Base Abilities
Abomination (Immortal) 
Apocalypse 
Captain America (Infinity War)
- with
teammate
Doombot 
Green Goblin 
Hulk (Immortal)

Jessica Jones 
Joe Fixit 
M.O.D.O.K. 
Ronan 
Scarlet Witch (Classic)

She-Hulk 
She-Hulk (Deathless) 
Spider-Man (Classic)

Spider-Man (Miles Morales) 
Spider-Man (Symbiote) 
Summoned Symbiote 
Symbiote Supreme 
Thing 
Titania 
Void 
Wasp 
Yondu

- Masteries
- Resonate Mastery
- Relics
- Synergies
- #Spider-Verse Heroes -
Mister Negative
with Spider-Man (Classic), (Stark Enhanced) or (Stealth Suit)
Hulk (Ragnarok)
- with Hercules
Human Torch
- with Invisible Woman or Super-Skrull, accompanied by Mister Fantastic and Thing
Kindred
- with Jack O'Lantern
Magneto
- with Kitty Pryde
Mister Fantastic
- with Invisible Woman or Super-Skrull, accompanied by Human Torch and Thing
Morbius
- with Jack O'Lantern
Okoye
- with Adam Warlock, Chee'ilth or The Serpent
Werewolf By Night
- with Jack O'Lantern
- Self-Inflicted
Passive[]
- Base Abilities
- Synergies
Champions -
Captain America (Infinity War)
with Captain America, Hulk or Hulk (Ragnarok)
- Self-Inflicted
List of Champions that counter Weakness[]
Reduced Potency[]
- Base Abilities
Patriot
- 76%
Purify (Specific to Weakness Debuffs)[]
- Base Abilities
Henchpool
- 58%
Trivia[]
Spider-Man (Classic)
no longer inflicts Weakness Debuffs after Update 38.2, except for the 1-Star version.
Captain Britain
no longer inflicts Weakness Debuffs after Update 51.0.